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In a retrospective review of hematopoietic stem cell transplantation for pre-treated patients with chronic lymphocytic leukemia, who have 17p deletion, three-year overall and progression-free survival were 44% and 37%, respectively. This matches favorably when compared to patients with the same chromosomal abnormality treated with chemotherapy alone.
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Recent studies have suggested that multiple myeloma and monoclonal gammopathy of unknown significance (MGUS) may predispose to venous thromboembolism, even in untreated patients.
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Low PSA levels do not assure the absence of prostate cancer.
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5-α reductase inhibitors and hip fracture in men; the effects of drug-reimbursement policy on outcomes; new guidelines for type 2 diabetes; beta-blocker-associated brady-cardia is linked to CVD events; FDA Updates.
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For young males cured of Hodgkin's Lymphoma, infertility is a significant issue.
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The dramatic reduction in in-stent restenosis (ISR) afforded by drug-eluting stents (DES) led to their widespread use throughout the world. Subsequently, more patients and lesions could be treated percutaneously with less thought about ISR. With the advent of a more widespread adoption of percutaneous coronary intervention, registry data began suggesting an increased risk of late and very late stent thrombosis with DES compared to bare-metal stents (BMS).
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The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico (GISSI)-Prevenzione trial demonstrated a lower mortality rate in post myocardial infarction patients treated with n-3 polyunsaturated fatty acids (PUFA) vs controls, which was mainly due to a reduction in sudden death.
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In this paper, Adabag et al from the Mayo Clinic analyzed the risk of sudden death after an acute myocardial infarction over a 28-year period in patients residing in Olmsted County, MN.
